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KMID : 0365819750150020283
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Journal of Pusan Medical College
1975 Volume.15 No. 2 p.283 ~ p.291
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A Clinical Observation of Choriocarcinoma in 26 Cases Admitted to the Busan National University Hospital from Jan. 1, 1972 to Oct. 31, 1975
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Abstract
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This study is dealing with choriocarcinoma patients admitted and treated at the Dept. of Ob-Gyn, Busan National University Hospital from Jan. 1, 1972 to Oct. 31, 1975.
Choriocarcinoma is a highly malignant tumor and has interesting immunological ramification, since it represents a neoplasm originating in the tissue of fetal trophoblast which has the ability to invade and destroy the tissue of another individual. Villous architecture is lost and the lesion consists of cytotrophoblastic and syncytiotrophoblastic elements in variable ratio. Choriocarcinoma metastasizes easily by hematogeneous route. Lungs, vagina, liver, and brain are frequently involved.
The following features are the summary of this study.
1. Choirocarcinoma occurred once in every 32.2 deliveries, respectively.
2. Age distribution showed the highest frequency between 26-30 year group (average 33.7 year).
3. Choriocarcinoma occurred more to the patients of group A blood consisting of 44.2%.
4. The frequency of nulliparity was 7.7% and that of primiparity was 26.9%, but the parity itself gave little significance as far as the occurence of choriocarcinoma is concerned.
5. 34.7% of all occurred after hydatidiform mole, 23.2% after abortion, and 15.4% after full term delivery.
6. Main symptoms of this dis´ase were vaginal bleeding, 80. 8%; lower abdominal pain and loss of appetite, 42.3% each; abdominal mass, 38.5%; dyspnea, 30.8% etc.
7. Metastasis confirmed at the time of admission was as follows-lungs, 76.9%; vagina, 26. 9%; pelvic wall, 15.3%; liver, 7.7%.
8. The highest remission may probably be obtained by combined therapy-hysterectomy and chemotherapy.
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KEYWORD
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